Insulin-like growth factor-I prevents hypoxia-inducible factor-1 alpha-dependent G1/S arrest by acti...
Insulin-like growth factor-I prevents hypoxia-inducible factor-1 alpha-dependent G1/S arrest by activating cyclin E/cyclin-dependent kinase2 via the phoshatidylinositol-3 kinase/AKT/forkhead box O1/Cdkn1b pathway in porcine granulosa cells
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Author / Creator
Li, Chengyu , Liu, Zhaojun , Zhou, Jiaqi , Meng, Xueqin , Liu, Shuo , Li, Weijian , Zhang, Xue , Zhou, Jilong , Yao, Wang , Dong, Chao , Cao, Yan , Li, Rongyang , Chen, Baobao , Jiang, Aiwen , Jiang, Yi , Ning, Caibo , Zhao, Fang , Wei, Yinghui , Sun, Shao-chen , Tao, Jingli , Wu, Wangjun , Shen, Ming and Liu, Honglin
Publisher
United States: Society for the Study of Reproduction
Journal title
Language
English
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Publisher
United States: Society for the Study of Reproduction
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Scope and Contents
Contents
As the follicle develops, the thickening of the granulosa compartment leads to progressively deficient supply of oxygen in granulosa cells (GCs) due to the growing distances from the follicular vessels. These conditions are believed to cause hypoxia in GCs during folliculogenesis. Upon hypoxic conditions, several types of mammalian cells have been...
Alternative Titles
Full title
Insulin-like growth factor-I prevents hypoxia-inducible factor-1 alpha-dependent G1/S arrest by activating cyclin E/cyclin-dependent kinase2 via the phoshatidylinositol-3 kinase/AKT/forkhead box O1/Cdkn1b pathway in porcine granulosa cells
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Record Identifier
TN_cdi_proquest_miscellaneous_2336983114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2336983114
Other Identifiers
ISSN
0006-3363
E-ISSN
1529-7268
DOI
10.1093/biolre/ioz162
