LRRK2 in Parkinson disease: challenges of clinical trials
LRRK2 in Parkinson disease: challenges of clinical trials
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
One of the most common monogenic forms of Parkinson disease (PD) is caused by mutations in the
LRRK2
gene that encodes leucine-rich repeat kinase 2 (LRRK2).
LRRK2
mutations, and particularly the most common mutation Gly2019Ser, are observed in patients with autosomal dominant PD and in those with apparent sporadic PD, who are clinically...
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Full title
LRRK2 in Parkinson disease: challenges of clinical trials
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TN_cdi_proquest_miscellaneous_2345506522
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2345506522
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ISSN
1759-4758
E-ISSN
1759-4766
DOI
10.1038/s41582-019-0301-2