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LRRK2 in Parkinson disease: challenges of clinical trials

LRRK2 in Parkinson disease: challenges of clinical trials

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2345506522

LRRK2 in Parkinson disease: challenges of clinical trials

About this item

Full title

LRRK2 in Parkinson disease: challenges of clinical trials

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Neurology, 2020-02, Vol.16 (2), p.97-107

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

One of the most common monogenic forms of Parkinson disease (PD) is caused by mutations in the
LRRK2
gene that encodes leucine-rich repeat kinase 2 (LRRK2).
LRRK2
mutations, and particularly the most common mutation Gly2019Ser, are observed in patients with autosomal dominant PD and in those with apparent sporadic PD, who are clinically...

Alternative Titles

Full title

LRRK2 in Parkinson disease: challenges of clinical trials

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2345506522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2345506522

Other Identifiers

ISSN

1759-4758

E-ISSN

1759-4766

DOI

10.1038/s41582-019-0301-2

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