Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
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Vogl, Annette M. , Phu, Lilian , Becerra, Raquel , Giusti, Sebastian A. , Verschueren, Erik , Hinkle, Trent B. , Bordenave, Martín D. , Adrian, Max , Heidersbach, Amy , Yankilevich, Patricio , Stefani, Fernando D. , Wurst, Wolfgang , Hoogenraad, Casper C. , Kirkpatrick, Donald S. , Refojo, Damian and Sheng, Morgan
Publisher
New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Neddylation is the post-translational protein modification most closely related to ubiquitination. Whereas the ubiquitin-like protein NEDD8 is well studied for its role in activating cullin−RING E3 ubiquitin ligases, little is known about other substrates. We developed serial NEDD8-ubiquitin substrate profiling (sNUSP), a method that employs
NED...
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Full title
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
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TN_cdi_proquest_miscellaneous_2350905625
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2350905625
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-019-0370-3
