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A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria

A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2353585313

A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria

About this item

Full title

A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2020-04, Vol.16 (4), p.415-422

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

In biotin biosynthesis, the conversion of pimeloyl intermediates to biotin is catalyzed by a universal set of four enzymes: BioF, BioA, BioD and BioB. We found that the gene homologous to
bioA
, the product of which is involved in the conversion of 8-amino-7-oxononanoate (AON) to 7,8-diaminononanoate (DAN), is missing in the genome of the cya...

Alternative Titles

Full title

A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2353585313

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2353585313

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-019-0461-9

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