Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress
Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Rationale
Depression and anxiety frequently co-occur, and this has important clinical implications. Previous studies showed that activation of the nociceptin/orphanin FQ receptor (NOP) elicits anxiolytic effects, while its blockade promotes consistent antidepressant actions. NOP antagonists are effective in reversing footshock-induced depressive...
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Full title
Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress
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TN_cdi_proquest_miscellaneous_2364046563
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2364046563
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ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-020-05487-y
