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Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing syste...

Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing syste...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2364048554

Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing system enhances its anti-tumor effect in melanoma in vitro and in vivo

About this item

Full title

Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing system enhances its anti-tumor effect in melanoma in vitro and in vivo

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Applied microbiology and biotechnology, 2020-04, Vol.104 (8), p.3517-3528

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

VNP20009, an attenuated mutant of
Salmonella,
is potentially applied for tumor therapy due to its specific accumulation and proliferation in the hypoxic zone of tumor. However, studies have shown that human immunity system and the associated toxicities of attenuated
Salmonella
evidently alleviated the anti-tumor effect when tumor is red...

Alternative Titles

Full title

Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing system enhances its anti-tumor effect in melanoma in vitro and in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2364048554

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2364048554

Other Identifiers

ISSN

0175-7598

E-ISSN

1432-0614

DOI

10.1007/s00253-020-10485-3

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