Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing syste...
Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing system enhances its anti-tumor effect in melanoma in vitro and in vivo
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Full title
Author / Creator
Wang, Huan , Chen, Tingtao , Wan, Linxi , Lu, Jiachen , Wei, Hong , Deng, Ke-Yu , Wei, Jing and Xin, Hong-Bo
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
VNP20009, an attenuated mutant of
Salmonella,
is potentially applied for tumor therapy due to its specific accumulation and proliferation in the hypoxic zone of tumor. However, studies have shown that human immunity system and the associated toxicities of attenuated
Salmonella
evidently alleviated the anti-tumor effect when tumor is red...
Alternative Titles
Full title
Attenuated Salmonella engineered with an apoptosis-inducing factor (AIF) eukaryotic expressing system enhances its anti-tumor effect in melanoma in vitro and in vivo
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2364048554
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2364048554
Other Identifiers
ISSN
0175-7598
E-ISSN
1432-0614
DOI
10.1007/s00253-020-10485-3