Identifying IGH disease clones for MRD monitoring in childhood B-cell acute lymphoblastic leukemia u...
Identifying IGH disease clones for MRD monitoring in childhood B-cell acute lymphoblastic leukemia using RNA-Seq
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Identifying patient-specific clonal IGH/TCR junctional sequences is critical for minimal residual disease (MRD) monitoring. Conventionally these junctional sequences are identified using laborious Sanger sequencing of excised heteroduplex bands. We found that the IGH is highly expressed in our diagnostic B-cell acute lymphoblastic leukemia (B-ALL)...
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Identifying IGH disease clones for MRD monitoring in childhood B-cell acute lymphoblastic leukemia using RNA-Seq
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TN_cdi_proquest_miscellaneous_2365196881
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2365196881
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-0774-4
