Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and...
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout
About this item
Full title
Author / Creator
Klück, Viola , van Deuren, Rosanne C , Cavalli, Giulio , Shaukat, Amara , Arts, Peer , Cleophas, Maartje C , Crișan, Tania O , Tausche, Anne-Kathrin , Riches, Philip , Dalbeth, Nicola , Stamp, Lisa K , Hindmarsh, Jennie Harré , Jansen, Tim L Th A , Janssen, Matthijs , Steehouwer, Marloes , Lelieveld, Stefan , van de Vorst, Maartje , Gilissen, Christian , Dagna, Lorenzo , Van de Veerdonk, Frank L , Eisenmesser, Elan Z , Kim, SooHyun , Merriman, Tony R , Hoischen, Alexander , Netea, Mihai G , Dinarello, Charles A and Joosten, Leo AB
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Subjects
More information
Scope and Contents
Contents
ObjectiveGout is characterised by severe interleukin (IL)-1-mediated joint inflammation induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine suppressing the activity of IL-1, we conducted genetic and functional studies aimed at elucidating the role of IL-37 in the pathogenesis and treatment of gout.MethodsVarian...
Alternative Titles
Full title
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout
Authors, Artists and Contributors
Author / Creator
van Deuren, Rosanne C
Cavalli, Giulio
Shaukat, Amara
Arts, Peer
Cleophas, Maartje C
Crișan, Tania O
Tausche, Anne-Kathrin
Riches, Philip
Dalbeth, Nicola
Stamp, Lisa K
Hindmarsh, Jennie Harré
Jansen, Tim L Th A
Janssen, Matthijs
Steehouwer, Marloes
Lelieveld, Stefan
van de Vorst, Maartje
Gilissen, Christian
Dagna, Lorenzo
Van de Veerdonk, Frank L
Eisenmesser, Elan Z
Kim, SooHyun
Merriman, Tony R
Hoischen, Alexander
Netea, Mihai G
Dinarello, Charles A
Joosten, Leo AB
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2369875227
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2369875227
Other Identifiers
ISSN
0003-4967,1468-2060
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2019-216233
