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A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2375905329

A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

About this item

Full title

A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2020-06, Vol.16 (6), p.660-666

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Nitric oxide synthase 3 (NOS3) produces the gasotransmitter nitric oxide (NO), which drives critical cellular signaling pathways by
S
-nitrosylating target proteins. Endogenous NOS3 resides at two distinct subcellular locations: the plasma membrane and the trans-Golgi network (TGN). However, NO generation arising from the activities of both t...

Alternative Titles

Full title

A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2375905329

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2375905329

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-020-0491-3

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