The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation
The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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The introduction of a trifluoromethyl (CF
3
) group can dramatically improve a compound’s biological properties. Despite the well-established importance of trifluoromethylated compounds, general methods for the trifluoromethylation of alkyl C–H bonds remain elusive. Here we report the development of a dual-catalytic C(
sp
3
)–H trifl...
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Full title
The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation
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TN_cdi_proquest_miscellaneous_2382655688
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2382655688
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-020-0436-1
