Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B...
Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential PI3K/AKT/mTOR signaling pathway inhibitors
About this item
Full title
Author / Creator
Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
In an attempt to search for new natural product-based antitumor agents, a series of novel (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole were designed and synthesized. The primary bioassay showed that compounds
5r
and
5s
presented certain inhibitory activity against cancer cells, weak cytotoxic activit...
Alternative Titles
Full title
Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential PI3K/AKT/mTOR signaling pathway inhibitors
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Record Identifier
TN_cdi_proquest_miscellaneous_2390652139
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2390652139
Other Identifiers
ISSN
1381-1991
E-ISSN
1573-501X
DOI
10.1007/s11030-020-10081-7
