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Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic anal...

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic anal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2398633427

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis

About this item

Full title

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2020-06, Vol.22 (6), p.630-639

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

How transplanted haematopoietic stem cells (HSCs) behave soon after they reside in a preconditioned host has not been studied due to technical limitations. Here, using single-cell RNA sequencing, we first obtained the transcriptome-based classifications of 28 haematopoietic cell types. We then applied them in conjunction with functional assays to t...

Alternative Titles

Full title

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2398633427

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2398633427

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-0512-1

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