p53: 800 million years of evolution and 40 years of discovery
p53: 800 million years of evolution and 40 years of discovery
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The evolutionarily conserved p53 protein and its cellular pathways mediate tumour suppression through an informed, regulated and integrated set of responses to environmental perturbations resulting in either cellular death or the maintenance of cellular homeostasis. The p53 and MDM2 proteins form a central hub in this pathway that receives stressfu...
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Full title
p53: 800 million years of evolution and 40 years of discovery
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TN_cdi_proquest_miscellaneous_2403029445
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2403029445
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/s41568-020-0262-1