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p53: 800 million years of evolution and 40 years of discovery

p53: 800 million years of evolution and 40 years of discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2403029445

p53: 800 million years of evolution and 40 years of discovery

About this item

Full title

p53: 800 million years of evolution and 40 years of discovery

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2020-08, Vol.20 (8), p.471-480

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The evolutionarily conserved p53 protein and its cellular pathways mediate tumour suppression through an informed, regulated and integrated set of responses to environmental perturbations resulting in either cellular death or the maintenance of cellular homeostasis. The p53 and MDM2 proteins form a central hub in this pathway that receives stressfu...

Alternative Titles

Full title

p53: 800 million years of evolution and 40 years of discovery

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2403029445

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2403029445

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/s41568-020-0262-1

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