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A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formatio...

A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2403029587

A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formation of breast cancer cells

About this item

Full title

A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formation of breast cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2020-06, Vol.39 (24), p.4728-4740

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

An epithelial to mesenchymal transition (EMT) is an embryonic dedifferentiation program which is aberrantly activated in cancer cells to acquire cellular plasticity. This plasticity increases the ability of breast cancer cells to invade into surrounding tissue, to seed metastasis at distant sites and to resist to chemotherapy. In this study, we hav...

Alternative Titles

Full title

A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formation of breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2403029587

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2403029587

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-020-1326-0

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