PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Tumor cells increase glucose metabolism through glycolysis and pentose phosphate pathways to meet the bioenergetic and biosynthetic demands of rapid cell proliferation. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) are key regulators of glucose metabolism via their synthesis of fructose-2,6-bisphosphate (F2,6BP), a...
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Full title
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
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TN_cdi_proquest_miscellaneous_2404046890
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404046890
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ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-020-03751-5