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PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404046890

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

About this item

Full title

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2020-07, Vol.470 (1-2), p.115-129

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Tumor cells increase glucose metabolism through glycolysis and pentose phosphate pathways to meet the bioenergetic and biosynthetic demands of rapid cell proliferation. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) are key regulators of glucose metabolism via their synthesis of fructose-2,6-bisphosphate (F2,6BP), a...

Alternative Titles

Full title

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2404046890

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404046890

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-020-03751-5

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