Legumain promotes fibrogenesis in chronic pancreatitis via activation of transforming growth factor...
Legumain promotes fibrogenesis in chronic pancreatitis via activation of transforming growth factor β1
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Author / Creator
Ren, Ying-Chun , Zhao, Qiuyan , He, Yan , Li, Bin , Wu, Zengkai , Dai, Juanjuan , Wen, Li , Wang, Xingpeng and Hu, Guoyong
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
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Scope and Contents
Contents
Chronic pancreatitis (CP) is a major risk factor for pancreatic cancer; however, little is known about the pathogenic mechanisms underlying the development of CP. Legumain (Lgmn) has been linked to some chronic inflammatory diseases. The present study investigated the role of legumain in pancreatic fibrogenesis. We induced CP in wild type C57BL6 (W...
Alternative Titles
Full title
Legumain promotes fibrogenesis in chronic pancreatitis via activation of transforming growth factor β1
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2404048334
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404048334
Other Identifiers
ISSN
0946-2716,1432-1440
E-ISSN
1432-1440
DOI
10.1007/s00109-020-01911-0
