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Small molecule 2′-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progen...

Small molecule 2′-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404048343

Small molecule 2′-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progenitors in vitro and their in vivo xeno-transplantation improves cardiac function

About this item

Full title

Small molecule 2′-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progenitors in vitro and their in vivo xeno-transplantation improves cardiac function

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2020-07, Vol.470 (1-2), p.99-113

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Small molecules are widely used to induce stem cell differentiation. 2′-deoxycytidine (2-DC) belongs to the cytidine family. It stimulates the expression of cardiac-specific genes and proteins, and directs mesenchymal stem cells towards cardiomyogenic differentiation. We aim to investigate the role of 2-DC-treated human umbilical cord mesenchymal s...

Alternative Titles

Full title

Small molecule 2′-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progenitors in vitro and their in vivo xeno-transplantation improves cardiac function

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2404048343

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2404048343

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-020-03750-6

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