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LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2409638652

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

About this item

Full title

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-06, Vol.582 (7810), p.115-118

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

During cell division, remodelling of the nuclear envelope enables chromosome segregation by the mitotic spindle
1
. The reformation of sealed nuclei requires ESCRTs (endosomal sorting complexes required for transport) and LEM2, a transmembrane ESCRT adaptor
2

4
. Here we show how the ability of LEM2 to condense on microtubules g...

Alternative Titles

Full title

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2409638652

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2409638652

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2232-x

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