LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
During cell division, remodelling of the nuclear envelope enables chromosome segregation by the mitotic spindle
1
. The reformation of sealed nuclei requires ESCRTs (endosomal sorting complexes required for transport) and LEM2, a transmembrane ESCRT adaptor
2
–
4
. Here we show how the ability of LEM2 to condense on microtubules g...
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Full title
LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
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TN_cdi_proquest_miscellaneous_2409638652
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2409638652
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2232-x