Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking
Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We sought to determine the significance of myeloid clonal hematopoiesis (CH) in the UK Biobank cohort (
n
= 502,524, median age = 58 years). Utilizing SNP array (
n
= 486,941) and whole exome sequencing data (
n
= 49,956), we identified 1166 participants with myeloid CH, defined by myeloid-associated mosaic chromosome abnormali...
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Full title
Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking
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TN_cdi_proquest_miscellaneous_2411534770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2411534770
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-0896-8
