Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson Disease
Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson Disease
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Mutations in the glucocerebrosidase (
GBA1
) gene are the most common genetic risk factor for Parkinson disease (PD). Homozygous or compound heterozygous
GBA1
mutations cause the lysosomal storage disorder Gaucher disease (GD), characterized by deficient activity of the glucocerebrosidase enzyme (GCase). Both individuals with GD type I...
Alternative Titles
Full title
Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson Disease
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Author / Creator
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TN_cdi_proquest_miscellaneous_2419423860
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2419423860
Other Identifiers
ISSN
1172-7047
E-ISSN
1179-1934
DOI
10.1007/s40263-020-00746-0
