Benzophenanthridine alkaloids suppress lung adenocarcinoma by blocking TMEM16A Ca2+-activated Cl− ch...
Benzophenanthridine alkaloids suppress lung adenocarcinoma by blocking TMEM16A Ca2+-activated Cl− channels
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
An increasing amount of evidence suggests that transmembrane member 16A (TMEM16A)-encoded Ca
2+
-activated Cl
−
channels play a crucial role in regulating tumorigenesis. Therefore, specific and potent TMEM16A inhibitors have been proposed to potentially be useful for the treatment of cancer. During drug screening, we found that benzophe...
Alternative Titles
Full title
Benzophenanthridine alkaloids suppress lung adenocarcinoma by blocking TMEM16A Ca2+-activated Cl− channels
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_2425594601
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2425594601
Other Identifiers
ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-020-02434-w
