Enantioselective in-vitro elimination kinetics of nerve agents in blood monitored by derivatization...
Enantioselective in-vitro elimination kinetics of nerve agents in blood monitored by derivatization and LC–MS/MS analysis
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
We present a simple method for chiral separation and analysis of organophosphorus nerve agents and apply it to monitor the enantioselective blood elimination kinetics of sarin in-vitro. The method is implemented in standard reverse phase LC–MS operating conditions, relieving the user of the dedicated operating conditions frequently demanded in chir...
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Full title
Enantioselective in-vitro elimination kinetics of nerve agents in blood monitored by derivatization and LC–MS/MS analysis
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TN_cdi_proquest_miscellaneous_2428066105
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2428066105
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ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-020-02854-8
