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Overexpression of pigment epithelium-derived factor in placenta-derived mesenchymal stem cells promo...

Overexpression of pigment epithelium-derived factor in placenta-derived mesenchymal stem cells promo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2428415977

Overexpression of pigment epithelium-derived factor in placenta-derived mesenchymal stem cells promotes mitochondrial biogenesis in retinal cells

About this item

Full title

Overexpression of pigment epithelium-derived factor in placenta-derived mesenchymal stem cells promotes mitochondrial biogenesis in retinal cells

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2021-01, Vol.101 (1), p.51-69

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Pigment epithelium-derived factor (PEDF) plays a role in protecting retinal pigment epithelial (RPE) cells from oxidative stress (OS), a causative factor of RPE cell death. Genetically modified mesenchymal stem cells (MSCs) can be used to treat critical and incurable retinal diseases. Here, we overexpressed PEDF in placenta-derived MSCs (PD-MSCsPED...

Alternative Titles

Full title

Overexpression of pigment epithelium-derived factor in placenta-derived mesenchymal stem cells promotes mitochondrial biogenesis in retinal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2428415977

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2428415977

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/s41374-020-0470-z

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