Generalizing RNA velocity to transient cell states through dynamical modeling
Generalizing RNA velocity to transient cell states through dynamical modeling
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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RNA velocity has opened up new ways of studying cellular differentiation in single-cell RNA-sequencing data. It describes the rate of gene expression change for an individual gene at a given time point based on the ratio of its spliced and unspliced messenger RNA (mRNA). However, errors in velocity estimates arise if the central assumptions of a co...
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Full title
Generalizing RNA velocity to transient cell states through dynamical modeling
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TN_cdi_proquest_miscellaneous_2430369771
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2430369771
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-020-0591-3
