Position-specific oxidation of miR-1 encodes cardiac hypertrophy
Position-specific oxidation of miR-1 encodes cardiac hypertrophy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease phenotypes
1
. One such modification, 8-oxoguanine
2
(o
8
G), is abundant in RNA
3
but its epitranscriptional role has not been investigated for microRNAs (miRNAs). Here we specifically sequence oxidized miRNAs in a rat model of the r...
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Full title
Position-specific oxidation of miR-1 encodes cardiac hypertrophy
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TN_cdi_proquest_miscellaneous_2431809263
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2431809263
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2586-0
