Distinct transcriptional programs of SOX2 in different types of small cell lung cancers
Distinct transcriptional programs of SOX2 in different types of small cell lung cancers
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Publisher
New York: Elsevier Inc
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Language
English
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Publisher
New York: Elsevier Inc
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Contents
SOX2 is recognized as an oncogene in human small cell lung cancer (SCLC), which is an aggressive neuroendocrine (NE) tumor. However, the role of SOX2 in SCLC is not completely understood, and strategies to selectively target SOX2 in SCLC cells remain elusive. Here, we show, using next-generation sequencing, that SOX2 expressed in the ASCL1-high SCL...
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Full title
Distinct transcriptional programs of SOX2 in different types of small cell lung cancers
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TN_cdi_proquest_miscellaneous_2434757974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2434757974
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/s41374-020-00479-0
