Recent insights how combined inhibition of immuno/proteasome subunits enables therapeutic efficacy
Recent insights how combined inhibition of immuno/proteasome subunits enables therapeutic efficacy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The proteasome is a multicatalytic protease in the cytosol and nucleus of all eukaryotic cells that controls numerous cellular processes through regulated protein degradation. Proteasome inhibitors have significantly improved the survival of multiple myeloma patients. However, clinically approved proteasome inhibitors have failed to show efficacy a...
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Recent insights how combined inhibition of immuno/proteasome subunits enables therapeutic efficacy
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TN_cdi_proquest_miscellaneous_2437120857
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2437120857
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ISSN
1466-4879,1476-5470
E-ISSN
1476-5470
DOI
10.1038/s41435-020-00109-1
