A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in pa...
A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in patients under highly active antiretroviral therapy
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
Highlights•Immune assays were performed on HIV-1 patients receiving therapeutic vaccine HIVAX. •HIVAX reduced the latent viral pool as measured by 2-LTR circles and total HIV-1 DNA. •HIVAX reduced serum cytokines and cellular markers of systemic immune activation. •HIVAX increased markers of activation on gag-specific CD4 + T cells. •HIVAX may supp...
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Full title
A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in patients under highly active antiretroviral therapy
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TN_cdi_proquest_miscellaneous_2439392634
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2439392634
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ISSN
0264-410X,1873-2518
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2020.04.015
