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Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smo...

Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2442598993

Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion

About this item

Full title

Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion

Publisher

England: Wiley Subscription Services, Inc

Journal title

Acta Physiologica, 2021-02, Vol.231 (2), p.e13558-n/a

Language

English

Formats

Publication information

Publisher

England: Wiley Subscription Services, Inc

More information

Scope and Contents

Contents

Aim
Abnormally activated vascular smooth muscle cells are key factors in pulmonary artery remodelling (PAR) and pulmonary artery hypertension (PAH). Keratin 1 is involved in inflammatory diseases; however, its role in PAH is unknown. We speculated that keratin 1 could regulate PASMCs and prevent PAH.
Methods
Rats were exposed to hypoxia (1...

Alternative Titles

Full title

Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2442598993

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2442598993

Other Identifiers

ISSN

1748-1708

E-ISSN

1748-1716

DOI

10.1111/apha.13558

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