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Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoieti...

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoieti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2444878570

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions

About this item

Full title

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2020-10, Vol.22 (10), p.1162-1169

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Stem cells need to be protected from genotoxic and proteotoxic stress to maintain a healthy pool throughout life
1

3
. Little is known about the proteostasis mechanism that safeguards stem cells. Here we report endoplasmic reticulum-associated degradation (ERAD) as a protein quality checkpoint that controls the haematopoietic stem cel...

Alternative Titles

Full title

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2444878570

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2444878570

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-00581-x

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