Integration of innate immune signalling by caspase-8 cleavage of N4BP1
Integration of innate immune signalling by caspase-8 cleavage of N4BP1
About this item
Full title
Author / Creator
Gitlin, Alexander D. , Heger, Klaus , Schubert, Alexander F. , Reja, Rohit , Yan, Donghong , Pham, Victoria C. , Suto, Eric , Zhang, Juan , Kwon, Youngsu C. , Freund, Emily C. , Kang, Jing , Pham, Anna , Caothien, Roger , Bacarro, Natasha , Hinkle, Trent , Xu, Min , McKenzie, Brent S. , Haley, Benjamin , Lee, Wyne P. , Lill, Jennie R. , Roose-Girma, Merone , Dohse, Monika , Webster, Joshua D. , Newton, Kim and Dixit, Vishva M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mutations in the death receptor FAS
1
,
2
or its ligand FASL
3
cause autoimmune lymphoproliferative syndrome, whereas mutations in caspase-8 or its adaptor FADD—which mediate cell death downstream of FAS and FASL—cause severe immunodeficiency in addition to autoimmune lymphoproliferative syndrome
4
–
6
. Mouse models h...
Alternative Titles
Full title
Integration of innate immune signalling by caspase-8 cleavage of N4BP1
Authors, Artists and Contributors
Author / Creator
Heger, Klaus
Schubert, Alexander F.
Reja, Rohit
Yan, Donghong
Pham, Victoria C.
Suto, Eric
Zhang, Juan
Kwon, Youngsu C.
Freund, Emily C.
Kang, Jing
Pham, Anna
Caothien, Roger
Bacarro, Natasha
Hinkle, Trent
Xu, Min
McKenzie, Brent S.
Haley, Benjamin
Lee, Wyne P.
Lill, Jennie R.
Roose-Girma, Merone
Dohse, Monika
Webster, Joshua D.
Newton, Kim
Dixit, Vishva M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2446665153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2446665153
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2796-5
