The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pathological degeneration of axons disrupts neural circuits and represents one of the hallmarks of neurodegeneration
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–
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. Sterile alpha and Toll/interleukin-1 receptor motif-containing protein 1 (SARM1) is a central regulator of this neurodegenerative process
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, and its Toll/interleukin-1 receptor (TIR) domain exerts...
Alternative Titles
Full title
The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
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TN_cdi_proquest_miscellaneous_2451381123
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2451381123
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2862-z
