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Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2452502578

Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

About this item

Full title

Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2021-04, Vol.21 (4), p.257-267

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Following their exit from the thymus, T cells are endowed with potent effector functions but must spare host tissue from harm. The fate of these cells is dictated by a series of checkpoints that regulate the quality and magnitude of T cell-mediated immunity, known as tolerance checkpoints. In this Perspective, we discuss the mediators and networks...

Alternative Titles

Full title

Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2452502578

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2452502578

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-020-00454-2

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