Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey
Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Following their exit from the thymus, T cells are endowed with potent effector functions but must spare host tissue from harm. The fate of these cells is dictated by a series of checkpoints that regulate the quality and magnitude of T cell-mediated immunity, known as tolerance checkpoints. In this Perspective, we discuss the mediators and networks...
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Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey
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TN_cdi_proquest_miscellaneous_2452502578
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2452502578
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/s41577-020-00454-2