IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentia...
IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis
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Author / Creator
Xu, Yanan , Huang, Xiaoyu , Li, Fengzhan , Liu, Tan , Yang, Tingting , Chen, Fei , Zhu, Jie , Pan, Meng , Zhang, Yong , Wang, Yuzhong , Fu, Linlin , Xiao, Chenghua and Geng, Deqin
Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
The transcription factor Blimp-1 is necessary for the B cell differentiation toward immunoglobulin-secreting plasma cells. However, the immunopathological mechanisms of Blimp-1 that regulates B cell differentiation remain unclear in MG. The purpose of this study was to perform a quantitative and functional analysis of Blimp-1 in MG. A total of 34 p...
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Full title
IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis
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Record Identifier
TN_cdi_proquest_miscellaneous_2457683621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2457683621
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ISSN
0257-277X
E-ISSN
1559-0755
DOI
10.1007/s12026-020-09164-2