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IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentia...

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2457683621

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis

About this item

Full title

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis

Publisher

New York: Springer US

Journal title

Immunologic research, 2021-02, Vol.69 (1), p.59-70

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

The transcription factor Blimp-1 is necessary for the B cell differentiation toward immunoglobulin-secreting plasma cells. However, the immunopathological mechanisms of Blimp-1 that regulates B cell differentiation remain unclear in MG. The purpose of this study was to perform a quantitative and functional analysis of Blimp-1 in MG. A total of 34 p...

Alternative Titles

Full title

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2457683621

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2457683621

Other Identifiers

ISSN

0257-277X

E-ISSN

1559-0755

DOI

10.1007/s12026-020-09164-2

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