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The nuclear export protein XPO1 — from biology to targeted therapy

The nuclear export protein XPO1 — from biology to targeted therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2459626058

The nuclear export protein XPO1 — from biology to targeted therapy

About this item

Full title

The nuclear export protein XPO1 — from biology to targeted therapy

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Clinical oncology, 2021-03, Vol.18 (3), p.152-169

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Exportin 1 (XPO1), also known as chromosome region maintenance protein 1, plays a crucial role in maintaining cellular homeostasis via the regulated export of a range of cargoes, including proteins and several classes of RNAs, from the nucleus to the cytoplasm. Dysregulation of this protein plays a pivotal role in the development of various solid a...

Alternative Titles

Full title

The nuclear export protein XPO1 — from biology to targeted therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2459626058

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2459626058

Other Identifiers

ISSN

1759-4774

E-ISSN

1759-4782

DOI

10.1038/s41571-020-00442-4

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