Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress
Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Filamentous actin (F-actin) provides cells with mechanical support and promotes the mobility of intracellular structures. Although F-actin is traditionally considered to be cytoplasmic, here we reveal that nuclear F-actin participates in the replication stress response. Using live and super-resolution imaging, we find that nuclear F-actin is polyme...
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Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress
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TN_cdi_proquest_miscellaneous_2466036448
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466036448
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-00605-6