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Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466036448

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

About this item

Full title

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2020-12, Vol.22 (12), p.1460-1470

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Filamentous actin (F-actin) provides cells with mechanical support and promotes the mobility of intracellular structures. Although F-actin is traditionally considered to be cytoplasmic, here we reveal that nuclear F-actin participates in the replication stress response. Using live and super-resolution imaging, we find that nuclear F-actin is polyme...

Alternative Titles

Full title

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2466036448

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2466036448

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-00605-6

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