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Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476129008

Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

About this item

Full title

Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

Publisher

Dordrecht: Springer Netherlands

Journal title

Molecular biology reports, 2021-01, Vol.48 (1), p.915-925

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Cyclin-dependent kinase (CDK) 4/6 inhibitors have emerged in the treatment of metastatic hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancer. However, most patients will eventually present disease progression, highlighting the inevitable resistance of cancer cells to CDK4/6 inhibition. Several s...

Alternative Titles

Full title

Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2476129008

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476129008

Other Identifiers

ISSN

0301-4851

E-ISSN

1573-4978

DOI

10.1007/s11033-020-06100-3

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