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Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assa...

Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476559602

Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assay for PD-L1 Transcripts in Circulating Tumor Cells

About this item

Full title

Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assay for PD-L1 Transcripts in Circulating Tumor Cells

Publisher

England: Oxford University Press

Journal title

Clinical chemistry (Baltimore, Md.), 2021-04, Vol.67 (4), p.642-652

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Background
PD-L1, an immune checkpoint protein, is an important biomarker for monitoring cancer patients during the administration of cancer immunotherapy. Droplet digital PCR (ddPCR), is a highly sensitive and accurate tool for the quantification of cancer biomarkers in liquid biopsy. We report the development and analytical validat...

Alternative Titles

Full title

Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assay for PD-L1 Transcripts in Circulating Tumor Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2476559602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2476559602

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1093/clinchem/hvaa321

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