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HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-ne...

HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2478595440

HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells

About this item

Full title

HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells

Publisher

New York: Springer US

Journal title

Breast cancer research and treatment, 2021-02, Vol.186 (1), p.37-51

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
Improved prognosis for triple-negative breast cancer (TNBC) has plateaued and the development of novel therapeutic strategies is required. This study aimed to explore the anti-tumor effect of combined eribulin and HDAC inhibitor (vorinostat: VOR, pan-HDAC inhibitor and ricolinostat: RICO, selective HDAC6 inhibitor) treatment for TNBC.

Alternative Titles

Full title

HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2478595440

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2478595440

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1007/s10549-020-06033-2

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