Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a...
Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload
About this item
Full title
Author / Creator
Publisher
Australia: Wiley Subscription Services, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Australia: Wiley Subscription Services, Inc
Subjects
More information
Scope and Contents
Contents
Interleukin‐11 (IL11) is important for fibroblast‐to‐myofibroblast transformations. Here, we examined the signalling and phenotypic effects of inhibiting IL11 signalling using neutralizing antibodies against IL11 or its cognate receptor (IL11RA) in a mouse model of acute and severe pressure overload. C57BL/6J mice underwent ascending aortic constri...
Alternative Titles
Full title
Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2479043604
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2479043604
Other Identifiers
ISSN
0305-1870,1440-1681
E-ISSN
1440-1681
DOI
10.1111/1440-1681.13458
