Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency
Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency
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Author / Creator
GRADS Investigators , Chu, Jen-hwa , Zang, Wenlan , Vukmirovic, Milica , Yan, Xiting , Adams, Taylor , DeIuliis, Giuseppe , Hu, Buqu , Mihaljinec, Antun , Schupp, Jonas C , Becich, Michael J , Hochheiser, Harry , Gibson, Kevin F , Chen, Edward S , Morris, Alison , Leader, Joseph K , Wisniewski, Stephen R , Zhang, Yingze , Sciurba, Frank C , Collman, Ronald G , Sandhaus, Robert , Herzog, Erica L , Patterson, Karen C , Sauler, Maor , Strange, Charlie and Kaminski, Naftali
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
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More information
Scope and Contents
Contents
BackgroundAlpha-1 antitrypsin deficiency (AATD) is a genetic condition that causes early onset pulmonary emphysema and airways obstruction. The complete mechanisms via which AATD causes lung disease are not fully understood. To improve our understanding of the pathogenesis of AATD, we investigated gene expression profiles of bronchoalveolar lavage...
Alternative Titles
Full title
Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency
Authors, Artists and Contributors
Author / Creator
Chu, Jen-hwa
Zang, Wenlan
Vukmirovic, Milica
Yan, Xiting
Adams, Taylor
DeIuliis, Giuseppe
Hu, Buqu
Mihaljinec, Antun
Schupp, Jonas C
Becich, Michael J
Hochheiser, Harry
Gibson, Kevin F
Chen, Edward S
Morris, Alison
Leader, Joseph K
Wisniewski, Stephen R
Zhang, Yingze
Sciurba, Frank C
Collman, Ronald G
Sandhaus, Robert
Herzog, Erica L
Patterson, Karen C
Sauler, Maor
Strange, Charlie
Kaminski, Naftali
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2483408781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2483408781
Other Identifiers
ISSN
0040-6376
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2019-214301
