The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer
The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Farnesoid X receptor (FXR) is a ligand-activated transcription factor involved in the control of bile acid (BA) synthesis and enterohepatic circulation. FXR can influence glucose and lipid homeostasis. Hepatic FXR activation by obeticholic acid is currently used to treat primary biliary cholangitis. Late-stage clinical trials investigating the use...
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Full title
The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer
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TN_cdi_proquest_miscellaneous_2488544328
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2488544328
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ISSN
1759-5045
E-ISSN
1759-5053
DOI
10.1038/s41575-020-00404-2
