Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells
Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells
About this item
Full title
Author / Creator
Sugata, Kenji , Matsunaga, Yukiko , Yamashita, Yuki , Nakatsugawa, Munehide , Guo, Tingxi , Halabelian, Levon , Ohashi, Yota , Saso, Kayoko , Rahman, Muhammed A. , Anczurowski, Mark , Wang, Chung-Hsi , Murata, Kenji , Saijo, Hiroshi , Kagoya, Yuki , Ly, Dalam , Burt, Brian D. , Butler, Marcus O. , Mak, Tak W. and Hirano, Naoto
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Peptide–major histocompatibility complex (pMHC) multimers enable the detection of antigen-specific T cells in studies ranging from vaccine efficacy to cancer immunotherapy. However, this technology is unreliable when applied to pMHC class II for the detection of CD4
+
T cells. Here, using a combination of molecular biological and immunologica...
Alternative Titles
Full title
Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2495406068
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2495406068
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-021-00836-4
