Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug devel...
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Drug development in cardiovascular disease is stagnating, with lack of efficacy and adverse effects being barriers to innovation. Human genetics can provide compelling evidence of causation through approaches such as Mendelian randomization, with genetic support for causation increasing the probability of a clinical trial succeeding. Mendelian rand...
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Full title
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development
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TN_cdi_proquest_miscellaneous_2501254682
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2501254682
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ISSN
1759-5002,1759-5010
E-ISSN
1759-5010
DOI
10.1038/s41569-020-00493-1
