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YAP-dependent proliferation by a small molecule targeting annexin A2

YAP-dependent proliferation by a small molecule targeting annexin A2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2501849490

YAP-dependent proliferation by a small molecule targeting annexin A2

About this item

Full title

YAP-dependent proliferation by a small molecule targeting annexin A2

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2021-07, Vol.17 (7), p.767-775

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The transcriptional coactivator Yes-associated protein 1 (YAP) orchestrates a proproliferative transcriptional program that controls the fate of somatic stem cells and the regenerative responses of certain tissues. As such, agents that activate YAP may hold therapeutic potential in disease states exacerbated by insufficient proliferative repair. He...

Alternative Titles

Full title

YAP-dependent proliferation by a small molecule targeting annexin A2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2501849490

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2501849490

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-021-00755-0

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