Design and development of novel inhibitors of aldo-ketoreductase 1C1 as potential lead molecules in...
Design and development of novel inhibitors of aldo-ketoreductase 1C1 as potential lead molecules in treatment of breast cancer
About this item
Full title
Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
Aldo–keto reductase 1C1 (AKR1C1) is a hydroxysteroid dehydrogenase, known to inactivate the biologically active progesterone into its corresponding 20 α-hydroxyprogesterone. Increased expression of the
AKR1C1
gene in oncogenesis is linked with resistance to various anticancer agents and hence it is considered as an emerging drug target for th...
Alternative Titles
Full title
Design and development of novel inhibitors of aldo-ketoreductase 1C1 as potential lead molecules in treatment of breast cancer
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2506275117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2506275117
Other Identifiers
ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-021-04134-0
