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The Influence of Bosentan on MicroRNA-27a/PPARγ/ET-1 Signaling Pathway in Pulmonary Artery Hypertens...

The Influence of Bosentan on MicroRNA-27a/PPARγ/ET-1 Signaling Pathway in Pulmonary Artery Hypertens...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2513244639

The Influence of Bosentan on MicroRNA-27a/PPARγ/ET-1 Signaling Pathway in Pulmonary Artery Hypertension

About this item

Full title

The Influence of Bosentan on MicroRNA-27a/PPARγ/ET-1 Signaling Pathway in Pulmonary Artery Hypertension

Publisher

New York: Springer US

Journal title

Pediatric cardiology, 2021-06, Vol.42 (5), p.1141-1148

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Pulmonary artery hypertension (PAH) is a common and serious disease which is characterized by pulmonary vascular remodeling. Bosentan (BST) is the first approved oral targeted drug of endothelin-1 (ET-1) receptor antagonists for the treatment of PAH. MicroRNA-27a (miR-27a) and peroxisome proliferator-activated receptor γ (PPARγ) were found to be re...

Alternative Titles

Full title

The Influence of Bosentan on MicroRNA-27a/PPARγ/ET-1 Signaling Pathway in Pulmonary Artery Hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2513244639

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2513244639

Other Identifiers

ISSN

0172-0643

E-ISSN

1432-1971

DOI

10.1007/s00246-021-02592-3

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