The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Antibiotics that target Gram-negative bacteria in new ways are needed to resolve the antimicrobial resistance crisis
1
–
3
. Gram-negative bacteria are protected by an additional outer membrane, rendering proteins on the cell surface attractive drug targets
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,
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. The natural compound darobactin targets the bacterial insert...
Alternative Titles
Full title
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase
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Record Identifier
TN_cdi_proquest_miscellaneous_2513246899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2513246899
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03455-w
