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PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergi...

PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2514599659

PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergic Asthma

About this item

Full title

PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergic Asthma

Publisher

New York: Springer US

Journal title

Inflammation, 2021-10, Vol.44 (5), p.1895-1907

Language

English

Formats

Publication information

Publisher

New York: Springer US

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Asthma is an inflammatory airway disease wherein bronchoconstriction, airway inflammation, and airway obstruction during asthma attacks are the main problems. It is recognized that imbalance of Th1/Th2 and Th17/Treg is a critical factor in asthma pathogenesis. Manipulation of these with signaling molecules such as mTOR, PI3K, Akt, and MyD88 can con...

Alternative Titles

Full title

PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergic Asthma

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2514599659

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2514599659

Other Identifiers

ISSN

0360-3997

E-ISSN

1573-2576

DOI

10.1007/s10753-021-01466-3

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