Heme catabolism by tumor-associated macrophages controls metastasis formation
Heme catabolism by tumor-associated macrophages controls metastasis formation
About this item
Full title
Author / Creator
Consonni, Francesca Maria , Bleve, Augusto , Totaro, Maria Grazia , Storto, Mariangela , Kunderfranco, Paolo , Termanini, Alberto , Pasqualini, Fabio , Alì, Chiara , Pandolfo, Chiara , Sgambelluri, Francesco , Grazia, Giulia , Santinami, Mario , Maurichi, Andrea , Milione, Massimo , Erreni, Marco , Doni, Andrea , Fabbri, Marco , Gribaldo, Laura , Rulli, Eliana , Soares, Miguel Parreira , Torri, Valter , Mortarini, Roberta , Anichini, Andrea and Sica, Antonio
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Although the pathological significance of tumor-associated macrophage (TAM) heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising anticancer therapy. Here we show that a distinct subset of TAMs (F4/80
hi
CD115
hi
C3aR
hi
CD88
hi
), endowed with high rates of heme catabolism by the stress-respon...
Alternative Titles
Full title
Heme catabolism by tumor-associated macrophages controls metastasis formation
Authors, Artists and Contributors
Author / Creator
Bleve, Augusto
Totaro, Maria Grazia
Storto, Mariangela
Kunderfranco, Paolo
Termanini, Alberto
Pasqualini, Fabio
Alì, Chiara
Pandolfo, Chiara
Sgambelluri, Francesco
Grazia, Giulia
Santinami, Mario
Maurichi, Andrea
Milione, Massimo
Erreni, Marco
Doni, Andrea
Fabbri, Marco
Gribaldo, Laura
Rulli, Eliana
Soares, Miguel Parreira
Torri, Valter
Mortarini, Roberta
Anichini, Andrea
Sica, Antonio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2518989437
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2518989437
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-00921-5
